For regenerative medicine research



It is a selective and potent inhibitor of ROCK (Rho-associated coiled-coil forming kinase/Rho binding kinase).Y-27632 has a variety of activities including vascular smooth muscle contraction through the ROCK signaling (Ki = 140 nmol/L p160ROCK). This product has been reported to suppress death of human ES cells and human iPS cells at the time of cell dispersion, and also improves viability of the cells after cryopreservation.

  • Y-27632 product grade
  • Reference data of preparation
  • Product List
  • Related Product List
  • Related Information

Y-27632 product grade

We provide four grades of Y-27632 products. You can select according to the purpose of uses.

ICHQ7 Mycoplasma Endotoxin Viable
Sterility Animal-
Y-27632 (GMP grade is coming soon) Y-27632 Y-27632 Y-27632 Y-27632 Y-27632 powder
Y-27632, MF** Y-27632 Y-27632 Y-27632 Y-27632 powder
CultureSure® Y-27632 Y-27632 Y-27632 Y-27632 powder
CultureSure® 10mmol/L
Y-27632 Solution, Animal-derived-free
Y-27632 Y-27632 Y-27632 Y-27632 liquid
Sterilized with filter

* Click to move to the PubMed Central® search results.
** We have a validation from the production to analysis and manage any changes for consistent, stable and high-quality production.

Reference data of preparation

The powder Y-27632 product has been confirmed to be soluble in water. After dilution, filter sterilize before use. Refer to the protocol at the top of this page for general usage in ES/iPS cell culture.

Amount of solvent when preparing solution

Y-27632 (powder)
1 mg 5 mg 10 mg
Concentration 1 mmol/L 2.956 mL 14.781 mL 29.562 mL
5 mmol/L 0.591 mL 2.956 mL 5.912 mL
10 mmol/L 0.296 mL 1.478 mL 2.956 mL
50 mmol/L 0.059 mL 0.296 mL 0.591 mL

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Products listed in the protocol

This product does not contain bFGF (basic Fibroblast Growth Factor).

Please use this product as a dish coating agent as needed.

Cytokine solutions

Related Information


  1. Cell Culture
  2. Stem Cell Culture
  3. Undifferentiated State Maintenance / Differentiation Induction
  • Small Molecules for ES/iPS cells Research
  • CultureSure® Small Molecules
  • StemSure® hPSC MediumΔ

For research use or further manufacturing use only. Not for use in diagnostic procedures.

Product content may differ from the actual image due to minor specification changes etc.

If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.


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