Wako和光纯药 低内毒素胶原蛋白和明胶 beMatrix Series
Low Endotoxin Collagen and Gelatin
beMatrix Series
Biomedical Research & Treatments
The past decade has seen major advances in the biomedical field, specifically in stem-cell research, regenerative medicine and transplantation. In response, cell therapy and gene therapy products are evolving at a corresponding pace. Nitta Gelatin’s beMatrix™ low endotoxin gelatin and collagen are specifically designed to meet the most stringent safety and quality specifications required for emerging biomedical applications. In addition to setting the industry gold-standard for low endotoxin levels, beMatrix™ Gelatin and Collagen are also sterilized using a proprietary method for the control of bacteria and viruses.
New techniques to combine cells with low endotoxin gelatin or collagen are leading the way in biomedical research and development. Recently, beMatrix™ Collagen AT was chosen as the material for a retinal pigment epithelial sheet in the first human clinical study based on iPS cells. In the field of regenerative medicine, beMatrix™ Gelatin was successfully used as the scaffolding material for the in-growth of new bone for osteoconductive implants.
在过去的十年里，生物医学领域取得了重大进展，特别是在干细胞研究、再生医学和移植方面。作为回应，细胞疗法和基因疗法产品也在以相应的速度发展。Nitta Gelatin 的 beMatrix™ 低内毒素明胶和胶原蛋白专门设计用于满足新兴生物医学应用所需的最严格的安全和质量规范。除了为低内毒素水平设定行业黄金标准外，beMatrix™ 明胶和胶原蛋白还使用专有方法进行消毒，以控制细菌和病毒。
将细胞与低内毒素明胶或胶原蛋白结合的新技术在生物医学研究和开发中处于领先地位。最近，在第一项基于 iPS 细胞的人体临床研究中，beMatrix™ 胶原蛋白 AT 被选为视网膜色素上皮层的材料。在再生医学领域，beMatrix™ 明胶成功用作骨传导植入物新骨向内生长的支架材料。
- Nitta Gelatin Website
- Manual & SDS
- beMatrix™ Gelatin
- beMatrix™ Collagen
- Product List
- Related Product List
- Related Information
beMatrix™ Gelatin
beMatrix™ Gelatin products are created using proprietary technology to yield unmatched safety and quality. Controlled for exceptionally low endotoxin levels and enhanced purity, beMatrix™ products are well suited for a range of biomedical applications including drug excipient, wound dressing materials, bone void fillers, and more.
Features
- Low endotoxin level: NMT 10 EU/g
- Virus inactivated
- IPEC-PQG GMP Compliant
- USP / EP (Ph. Eur.) / JP Compliant
- DMF / MAF registered
- Storage Condition: Room temperature
- Expiration date: 3 years from date of manufacture
- Safety Test performed
Test Item Cytotoxicity Sensitization Intradermal Reaction Pyrogen Antigenicity Result Negative Negative Negative Negative Negative
beMatrix™ Gelatin LS-H
Features
- Alkaline-treated gelatin derived from porcine skin
- High Gel Strength (about 300g)
beMatrix™ Gelatin LS-250
Features
- Sterilized alkaline-treated gelatin derived from porcine skin
- High Gel Strength (about 250g)
- Designed for higher density and faster gelation
beMatrix™ Gelatin LS-W
Features
- Alkaline-treated gelatin derived from porcine skin
- Low Gel Strength (about 100g)
beMatrix™ Gelatin HG
Features
- Sterilized gelatin hydrolyzate derived from porcine skin
- Acute Systemic Toxicity: Negative
- Subacute Toxicity: Negative
beMatrix™ Collagen
The first collagen product used in the world’s first iPS cells based transplant.
beMatrix™ Collagen was used for culturing retinal cells derived from iPS cells that were used for treatment of “age-related macular degeneration”. Cultured cells were successfully transplant in patient without canceration, becoming the world first case.
beMatrix™ Collagen is High quality collagen with strict endotoxin control and virus inactivating processing.
beMatrix™ Collagen AT
Features
- Acid extracted collagen solution derived from porcine tendon
- Low endotoxin level: NMT 0.5 EU/mL
- Storage Condition: Cold storage [4 °C to 8 °C]
- Expiration date: 2 years from the date of manufacture
- Concentration: 3 mg/mL, pH 3
beMatrix™ Collagen TE
Features
- Pepsin-solubilized collagen solution derived from porcine skin
- Low endotoxin level: NMT 0.5 EU/mL
- Storage Condition: Cold storage [4 °C to 8 °C]
- Expiration date: 2 years from the date of manufacture
- Concentration: 5 mg/mL, pH 3
beMatrix™ Collagen FD
Features
- Freeze-dried atelocollagen derived from porcine skin
- Low endotoxin level: NMT 100 EU/g
- Storage Condition: Room temperature
- Expiration date: 2 years from the date of manufacture
Product Appearance
- Spongiform
- Size: approx. 140 x 100 x 10 mm
Application
- Scaffold
- Cell culture / transplantation
- Electro-spinning etc.
beMatrix™ 胶原蛋白 TE
特征
- 源自猪皮的胃蛋白酶溶解胶原蛋白溶液
- 低内毒素水平：NMT 0.5 EU/mL
- 储存条件：冷藏[4°C至8°C]
- 保质期：自生产之日起2年
- 浓度：5 毫克/毫升，pH 3
beMatrix™ 胶原蛋白FD
特征
- 源自猪皮的冻干去端肽胶原
- 低内毒素水平：NMT 100 EU/g
- 储存条件：室温
- 保质期：自生产之日起2年
产品外观
- 海绵状
- 尺寸：约 140 x 100 x 10 毫米
应用
- 脚手架
- 细胞培养/移植
- 静电纺丝等
Product List
beMatrix Gelatin
beMatrix™ Gelatin HG
- Manufacturer : Nitta Gelatin Inc.
- Storage Condition : Keep below 25 degrees C.
- Notes on Purchasing :
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10g
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beMatrix™ Gelatin LS-H
- Manufacturer : Nitta Gelatin Inc.
- Storage Condition : Keep at RT.
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10g
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beMatrix™ Gelatin LS-W
- Manufacturer : Nitta Gelatin Inc.
- Storage Condition : Keep at RT.
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10g
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beMatrix™ Gelatin LS-250
- Manufacturer : Nitta Gelatin Inc.
- Storage Condition : Keep below 25 degrees C.
- Notes on Purchasing :
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10g
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beMatrix Collagen
beMatrix™ Collagen AT
- Manufacturer : Nitta Gelatin Inc.
- Storage Condition : Keep at 2-10 degrees C.
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100mL
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beMatrix™ Collagen FD
- Manufacturer : Nitta Gelatin Inc.
- Storage Condition : Keep at RT.
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1g
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beMatrix™ Collagen TE
- Manufacturer : Nitta Gelatin Inc.
- Storage Condition : Keep at 2-10 degrees C.
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100mL
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beMatrix Gelatin
beMatrix Collagen
Related Product List
Low Endotoxin Gelatin
Low Endotoxin Collagen
Other Products of Nitta Gelatin
Related Information
Category
- Cell Culture
- Animal Cell Culture
- Biomaterial
- Cell Culture
- Stem Cell Culture
- Extracellular Matrix / Cell Coating
- Cell Culture
- Cell Culture Plasticware
- Extracellular Matrix / Cell Coating
- Pharma Manufacturing & QC
- Raw Material
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