日本老化Jaica-Anti 4-HHE monoclonal antibody

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Rev.070713

Suitable for immunohistocheistry. For research use only.

About 4-hydroxy-2-hexenal (4-HHE)

4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts. This antibody is specific for HHE-histidine Michael adduct (HHE-His) and enable to detect HHE-His in the tissue samples.

Specifications

Clone #:

HHE53

Antigen:

HHE-modified keyhole-lympet hemocyanine

Specificity:

Specific for HHE-modified protein (especially HHE-His Michael adduct)

Subclass:

Mouse IgG_{1 kappa}
Prepared as ascite, and protein-A purified.

Form:

Frozen in 10mM PBS containing 0.1% NaN₃ and 0.5% BSA.

Application:

Immunohistochemistry；It is recommended that the antibody be tried at 0.5-1.0 µg/mL on paraformaldehyde fixed tissue.

Storage:

Less than -20°C

Specifity of anti 4-HHE antibody.

Product name	Code	Content
Anti 4-HHE monoclonal antibody	MHH-030n	30 µg IgG

Manufactured by NOF corporation, Japan.

If you are in the U.S., please click here
to Genox Corporation (Los Angeles, CA).

Instruction manual (PDF)

Technical information

[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.

We are making efforts to prevent errors or mistakes on preparing web site documents, instruction manuals and products.
But even if some damage would causedby such faults, we will be exempt from responsibility.

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日本衰老控制研究所 Japan Institute For the Control of Aging (JaICA) 专注于衰老研究领域。提供DNA氧化损伤检测试剂盒，并且处于该领域的领先地位。JaICA氧化应激相关产品：DNA氧化损伤检测、脂质氧化检测、蛋白氧化检测、抗氧化分析，以及微量元素分析。详情请咨询JaICA中国区代理商：上海金畔生物科技有限公司。