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Rev.160826 |
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| Suitable for immunohistocheistry. For research use only. |
| About malondialdehyde (MDA) |
| Malondialdehyde (MDA) is one of the major aldehyde derive from lipid peroxidation. MDA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with MDA and lysine residue leads to the formation of numerous numbers of adducts, such as dihydropyridine-lysine (DHP-lysine) type derivative. This monoclonal antibody is specific for the MDA-modified protein, especially DHP-lysine type derivative. |
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| Specifications |
| Clone #: |
1F83 |
| Antigen: |
MDA-modified keyhole-lympet hemocyanine. |
| Form: |
Frozen (100 µg/mL antibody in 10mM PBS containing 0.1% NaN3 and 0.5% BSA). Purified by Protein-A. |
| Application: |
Immunohistochemistry.
Recommended antibody concentration is 0.5-1.0 µg/mL on paraformaldehyde fixed tissue. |
| Specificity: |
MSpecific for MDA-modified protein (especially DHP-lysine). |
| Subclass: |
Mouse IgG2a(lambda) |
| Storage: |
Less than -20°C |
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| Specificity of anti MDA antibody. |
Immunohistochemical detection of MDA-modified protein in atherosclerotic aorta.
Dr. N Shibata, Tokyo Women’s Medical University. |
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| References |
| 1) |
Immunochemical detection of a lipofuscin-like fluorophore derivered from malondialdehyde and lysine.
S Yamada, S Kumazawa, T Ishii, T Nakayama, K Itakura, N Shibata, M Kobayashi, K Sakai, T Osawa and K Uchida.
J.Lipid Res. 42, p1187-1196 (2001) |
| 2) |
Investigation on the Origin of Sperm DNA Fragmentation: Role of Apoptosis, Immaturity and Oxidative Stress.
Muratori M, Tamburrino L, Marchiani S, Cambi M, Olivito B, Azzari C, Forti G, Baldi E
Mol Med. 21,p109-122(2015). doi: 10.2119/molmed.2014.00158. |
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| Product name |
Code |
Content |
| Anti Malondialdehyde (MDA) monoclonal antibody |
MMD-030n |
30 µg IgG |
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Manufactured by NOF corporation, Japan.
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If you are in the U.S., please click here
to Genox Corporation (Los Angeles, CA).
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| Instruction manual (PDF) |
Technical information |
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| [NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
We are making efforts to prevent errors or mistakes on preparing web site documents, instruction manuals and products.
But even if some damage would be caused by such faults, we will be exempt from responsibility. |
日本衰老控制研究所 Japan Institute For the Control of Aging (JaICA) 专注于衰老研究领域。提供DNA氧化损伤检测试剂盒，并且处于该领域的领先地位。JaICA氧化应激相关产品：DNA氧化损伤检测、脂质氧化检测、蛋白氧化检测、抗氧化分析，以及微量元素分析。详情请咨询JaICA中国区代理商：上海金畔生物科技有限公司。
