标签归档：Irvine欧文

Irvine欧文 PRIME-XV NK Cell CDM 代理,91215 NK细胞培养基

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PRIME-XV NK Cell CDM

Irvine欧文-NK细胞培养基 (91215 – PRIME-XV NK Cell CDM),化学成分限定的配方:含有重组白蛋白,但不含血浆衍生白蛋白,无动物成分,不含抗生素,不含酚红,支持NK(自然杀伤细胞)和NKT(自然杀伤T细胞)细胞扩增。

货号:91215

用于自然杀伤细胞离体扩增的化学成分限定的、无动物源成分的cGMP级别培 养基。这种先进的配方设计用于基于NK和NKT细胞的免疫疗法研究和转化应 用,在保持NK和NKT细胞功能和效力的同时提供生长,无需补充血清。

·批次间一致性

·将外源的病原体的风险降至

·配方可支持源自外周血单核细胞的NK和NKT细胞

促进从实验室到进一步制造用途的无缝过渡:

·强大的原材料控制和供应链管理

·提供分析证书、原产地证书和向FDA提交的药物主文件

·广泛的QA测试,包括功能性、无菌性和内毒素

货号 产品名称 状态 规格 储存条件 保质期
91215 PRIME-XV NK Cell CDM 液体 1L 本产品在 2-8°C 下运输。 收到后,立即储存在 2-8°C 并避光。 使用无菌技术处理以避免污染。未开封的液体培养基自生产之日起可稳定保存12 个月。
有或无饲养层细胞的情况下,都可以保留NK细胞形态

Details
PRIME-XV NK Cell CDM is the first commercially-available, chemically defined, and animal component-free medium for the ex vivo expansion of NK and NKT cells.

Designed for use in NK and NKT cell-based immunotherapy research and translational applications, this advanced formulation delivers growth while maintaining NK and NKT cell functionality and potency – without the need for serum supplementation.

Provides Optimal Performance
Chemically defined, animal component-free natural killer cell culture medium

Supports robust cell expansion and viability in heterogeneous PBMC culture enriched for CD56+ cells
Supports expansion of NK cells when supplemented with IL-2, IL-12, IL-18, and IL-21
Supports NKT cell expansion when supplemented with IL-2
Maintains high NK and NKT cytotoxic capability
Designed and manufactured to facilitate transfer from research to clinic. Supported by robust raw material controls and supply chain management

FDA, Federal, and State registered – cGMP-compliant manufacture
EN ISO 13485:2016 certified
MDSAP certified
Extensive QC testing including functionality, sterility (USP <71>), endotoxin (USP <85>), and mycoplasma (USP <63>)
Drug Master Files (DMFs) filed with the FDA – available upon request

Specifications
Storage
This product is shipped at 2-8°C with cold packs. Upon receipt, store immediately at 2-8°C and protect from light.
Shelf Life
Unopened liquid medium is stable for 18 months from date of manufacture, as indicated on the label, when stored at 2-8°C and protected from light. Once opened, the product should be stored at 2-8°C in the dark and used within 4 weeks.

Irvine欧文PRIME-XV FreezIS,91139 含10% DMSO的细胞冻存液

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PRIME-XV FreezIS(含10%DMSO)

Irvine欧文-含10% DMSO的细胞冻存液(91139 – PRIME-XV FreezIS),含DMSO的细胞冻存液,无蛋白、无血清、化学成分限定、无动物成分,针对HSC(造血干细胞)、T细胞、NPC(神经元前体细胞)、iPSC(诱导性多功能干细胞)和CHO(中国仓鼠卵巢细胞)等细胞,支持在-80℃至-196℃ 环境下保存多种细胞类型,同时保持解冻后细胞的细胞表面标记物表达。

货号:91139 用于细胞和组织的无蛋白质、化学成分限定的低温保存溶液

·可在-80°C至-196°C环境下保存多种细胞类型

·维持解冻后细胞的细胞表面标志物表达

·不需要额外的成分

·在cGMP条件下制造

·药物主文件(DMF)注册

货号 产品名称 状态 规格 储存条件 保质期
91139 PRIME-XV FreezIS 液体 10mL,100mL 在2-8°C下运输。 收到后立即储存在2-8°C并避光。 使用无菌技术处理。未开封的液体培养基自生产之日起可稳定保存12个月。

较高的复苏后细胞活率和回收率

与含DMSO的溶液相比,PRIME-XV MSC FreezIS DMSO-FREE保留了相当的MSCs活率和细胞扩增 特征。

来自脂肪组织(AD-MSC)、骨·(BM-MSC)和脐带 (UC-MSC)的MSCs在PRIME-XV MSC FreezIS DMSO-FREE和含DMSO的PRIME-XV FreezIS冷冻 溶液中冷冻。将细胞在液氮中储存两天,然后复苏 并通过两次传代培养,直至80%汇合。用台盼蓝染 色评估活率(A)和细胞密度(B)。可根据要求提供 长期冻存数据。

Protein-free, animal component-free, chemically defined cryopreservation solution

Enables cell preservation for short-term at -80°C and long-term storage in liquid nitrogen to -196°C
High post-thaw viability and growth
Maintains cell surface marker expression of mesenchymal stem cells (MSCs) and T cells post-thaw
Complete, ready-to-use medium
Contains DMSO in the formulation
Designed and manufactured to facilitate transfer from research to clinic. Supported by robust raw material controls and supply chain management.

FDA, Federal, and State registered – cGMP-compliant manufacture
EN ISO 13485:2016 certified
MDSAP certified
Extensive QC testing including functionality, sterility (USP <71>), endotoxin (USP <85>), and mycoplasma (USP <63>)
Drug Master Files (DMFs) filed with the FDA – available upon request

HEK293 补料培养基BalanCD HEK293 Feed 91166,Irvine欧文

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BalanCD HEK293 System

FUJIFILM Irvine Scientific的BalanCD HEK293可扩展系统提供了生长 和生产之间的 平衡,可 限度地提高哺乳动物细胞培养的生产力。

该多功能系统由化学成分明确、无动物源成分的BalanCD HEK293培养基和BalanCD HEK293 Feed组成,支持一系列应用,包括生产用于基因 的病毒载体、瞬时蛋白表达和重组蛋白生产。

·化学成分明确,不含动物源成分

·快速、可放大生产,用于生物生产的病毒载体和蛋白质

·支持用于各种HEK293细胞系

·提高瞬时蛋白质表达的生产力

·摇瓶、转瓶和生物反应器

BalanCD HEK293 Feed

Irvine欧文- HEK293 补料培养基(91166 – BalanCD HEK293 Feed),293补料,无血清、无动物源、化学成分限定。用于提高悬浮驯化293细胞的转染后蛋白产量。

货号:91166 BalanCD HEK293 Feed的配方可显着提高转染后驯化悬浮的 HEK293细胞系的蛋白质产量。

·增加活细胞密度和培养时间,以 化产率

·适用于各种HEK293细胞系

货号 产品名称 状态 规格 储存条件 保质期
91166 BalanCD® HEK293 Feed 液体 500mL 2–8℃, 避光 1年

Details
BalanCD HEK293 Feed is formulated to significantly increase protein yields in suspension-adapted HEK293 cell lines post-transfection.

Increase viable cell density and culture duration to maximize yield
Use the same Feed for a wide range of HEK293 cell lines
Fulfill regulatory requirements

Chemically-defined, animal component-free formula
Drug Master File (DMF) submitted to US FDA
Two-fold increase in titer compared to other commercially-available media

HEK293-6E cells were cultured in duplicate 125mL Erlenmeyer flasks with a 30 mL working volume. Cells were seeded at 3 x 105 cells/mL in BalanCD HEK 293 medium. PEI-mediated transfection was performed on day 3 to produce a biosimilar antibody. BalanCD HEK293 medium was supplemented with a 5% v/v addition of BalanCD HEK293 Feed on days 1-4 post-transfection.  Protein titer was measured on days 7, 9, and 11 post-transfection. Cultures terminated when viability dropped below 70%, (data not shown). Data shown represents the average of two duplicate cultures.

Specifications
Storage
Store at 2-8°C
Shelf Life
1 year from date of manufacture

91150 Anti-Clumping Supplement,Irvine欧文-抗细胞结团剂

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Anti-Clumping Supplement

Irvine欧文-抗细胞结团剂(91150 – Anti-Clumping Supplement),不含动物成分,不含酶,通过防止细胞聚集提高生产力。支持多种细胞,包括CHO、HEK293、杂交瘤和昆虫细胞。

货号:91150 作为BalanCD Transfectory CHO系统的一部分,抗结团剂是一种不含 动物源成分和酶的细胞培养基补充剂,旨在减少悬浮培养中各种细胞 类型的细胞聚集。

货号 产品名称 状态 规格 储存条件 保质期
91150 Anti-Clumping Supplement 液体 50mL 2–8℃, 避光 1年

Details
Part of the BalanCD system of media and supplements, the Anti-Clumping Supplement is an animal-component- and enzyme-free supplement to cell culture medium, designed to reduce cell aggregation for various cell types in suspension culture.

Specifications
Storage
Store at 2-8°C
Shelf Life
2 years from date of manufacture